Invention Application
WO2008064337A2 BENZOCYCLOHEPTYL ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR ACTIVITY
审中-公开
具有丝氨酸1-磷酸酯受体活性的苯并咪唑类似物
- Patent Title: BENZOCYCLOHEPTYL ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR ACTIVITY
- Patent Title (中): 具有丝氨酸1-磷酸酯受体活性的苯并咪唑类似物
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Application No.: PCT/US2007/085433Application Date: 2007-11-21
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Publication No.: WO2008064337A2Publication Date: 2008-05-29
- Inventor: LYNCH, Kevin, R. , MACDONALD, Timothy, L.
- Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION , LYNCH, Kevin, R. , MACDONALD, Timothy, L.
- Applicant Address: 250 West Main Street, Suite 300 Charlottesville, VA 22902 US
- Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION,LYNCH, Kevin, R.,MACDONALD, Timothy, L.
- Current Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION,LYNCH, Kevin, R.,MACDONALD, Timothy, L.
- Current Assignee Address: 250 West Main Street, Suite 300 Charlottesville, VA 22902 US
- Agency: PROUT, William, F.
- Priority: US60/860,781 20061121; US60/956,354 20070816
Abstract:
Benzocycloheptyl analogs that have agonist activity at one or more of the S IP receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at SlP receptors.
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