Invention Application
WO2008071695A1 R-HNL RANDOM VARIANTS AND THEIR USE FOR PREPARING OPTICALLY PURE, STERICALLY HINDERED CYANOHYDRINS
审中-公开
R-HNL随机变量及其用于制备光学纯的，异味的氰基氰
- Patent Title: R-HNL RANDOM VARIANTS AND THEIR USE FOR PREPARING OPTICALLY PURE, STERICALLY HINDERED CYANOHYDRINS
- Patent Title (中): R-HNL随机变量及其用于制备光学纯的，异味的氰基氰
-
Application No.: PCT/EP2007/063692Application Date: 2007-12-11
-
Publication No.: WO2008071695A1Publication Date: 2008-06-19
- Inventor: GLIEDER, Anton
- Applicant: DSM IP ASSETS BV , GLIEDER, Anton
- Applicant Address: Het Overloon 1 NL-6411 TE Heerlen NL
- Assignee: DSM IP ASSETS BV,GLIEDER, Anton
- Current Assignee: DSM IP ASSETS BV,GLIEDER, Anton
- Current Assignee Address: Het Overloon 1 NL-6411 TE Heerlen NL
- Agency: SEIBEL-THOMSEN, Nadja
- Priority: ATA 20061214; EP07016544.4 20070823
- Main IPC: C12N9/88
- IPC: C12N9/88 ; C12P13/00 ; C12P41/00
Abstract:
The invention relates to R -hydroxynitrile lyases with improved substrate acceptance, increased activity and increased selectivity, obtainable by introducing random mutations with the aid of random mutagenesis and/or saturation mutagenesis techniques, identifyingby means of screening or selection and, where appropriate, subsequently combining advantageous mutations, and to the use thereof.
Information query
