A process transmitter (12) for sensing a process variable of a process fluid includes a process sensor (30), transmitter circuitry (40), a transmitter housing (38) and a transmitter mounting component (33, 44A, 44B). The process sensor (30) senses the process variable of the process fluid and the transmitter circuitry (40) processes a signal from the process sensor (30). The transmitter housing (38) receives the process sensor (30) and transmitter circuitry (40), and the transmitter mounting component (33, 44A, 44B) isolates the sensor (30) or the transmitter circuitry (40) from the process fluid or external environment. The mechanical integrity sensor (46A, 46B, 52A, 52B) validates assembly of the transmitter housing (38) and transmitter mounting component (33, 44A, 44B).