Invention Application
- Patent Title: METHOD AND APPARATUS FOR GENDER SELECTION BASED ON PH
- Patent Title (中): 基于PH的性别选择方法与设备
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Application No.: PCT/US2007/083235Application Date: 2007-10-31
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Publication No.: WO2008088601A2Publication Date: 2008-07-24
- Inventor: PRIEN, Samuel, D. , PENROSE, Lindsay, L.
- Applicant: TEXAS TECH UNIVERSITY SYSTEM , PRIEN, Samuel, D. , PENROSE, Lindsay, L.
- Applicant Address: Office Of Technology Transfer And Intellectual Property P.o. Box 42007 Lubbock, TX 79409-2007 US
- Assignee: TEXAS TECH UNIVERSITY SYSTEM,PRIEN, Samuel, D.,PENROSE, Lindsay, L.
- Current Assignee: TEXAS TECH UNIVERSITY SYSTEM,PRIEN, Samuel, D.,PENROSE, Lindsay, L.
- Current Assignee Address: Office Of Technology Transfer And Intellectual Property P.o. Box 42007 Lubbock, TX 79409-2007 US
- Agency: FLORES, Edwin et al.
- Priority: US60/885,045 20070116
- Main IPC: C12N5/06
- IPC: C12N5/06
Abstract:
The present invention includes methods and apparatus to separate X or Y-chromosome bearing sperm cells in a population by first placing the population of sperm cells at physiological pH environment, and simultaneously contacting the population of sperm cells with one or more additional sub-environments with different pH values. The exposure allows mobile sperm cells bearing X or Y-chromosome to migrate to the different pH sub-environments, wherein each cell only exposed or come in contact with one pH sub-environment. Finally, the collecting X or Y- chromosome enriched population of sperm cells is performed.
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