Embodiments of systems and methods for tuning a turbine are provided. In one embodiment, a method may include receiving at least one of a measured operating parameter or a modeled operating parameter of a turbine during operation; and tuning the turbine during operation. The turbine may be tuned during operation by applying the measured operating parameter or modeled operating parameter or parameters to at least one operational boundary model, applying the measured operating parameter or modeled operating parameter or parameters to at least one scheduling algorithm, comparing the output of the operational boundary model or models to the at output of the scheduling algorithm or algorithms to determine at least one error term, and closing loop on the one error term or terms by adjusting at least one turbine control effector during operation of the turbine.