Invention Application
WO2008138843A1 IMIDAZOPYRIDINES AND TRIAZOLOPYRIMIDINES USEFUL FOR THE TREATMENT OF JOINT DEGENERATIVE & INFLAMMATORY DISEASES
审中-公开
用于治疗联合变应性和炎症性疾病的咪达唑啶和三唑来膦酸
- Patent Title: IMIDAZOPYRIDINES AND TRIAZOLOPYRIMIDINES USEFUL FOR THE TREATMENT OF JOINT DEGENERATIVE & INFLAMMATORY DISEASES
- Patent Title (中): 用于治疗联合变应性和炎症性疾病的咪达唑啶和三唑来膦酸
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Application No.: PCT/EP2008/055651Application Date: 2008-05-07
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Publication No.: WO2008138843A1Publication Date: 2008-11-20
- Inventor: ANDREWS, Martin James Inglis , CHAMBERS, Mark Stuart , SCHMIDT, Wolfgang , BAR, Grégory Louis Joseph
- Applicant: GALAPAGOS N.V. , ANDREWS, Martin James Inglis , CHAMBERS, Mark Stuart , SCHMIDT, Wolfgang , BAR, Grégory Louis Joseph
- Applicant Address: Generaal De Wittelaan L11/A3 B-2800 Mechelen BE
- Assignee: GALAPAGOS N.V.,ANDREWS, Martin James Inglis,CHAMBERS, Mark Stuart,SCHMIDT, Wolfgang,BAR, Grégory Louis Joseph
- Current Assignee: GALAPAGOS N.V.,ANDREWS, Martin James Inglis,CHAMBERS, Mark Stuart,SCHMIDT, Wolfgang,BAR, Grégory Louis Joseph
- Current Assignee Address: Generaal De Wittelaan L11/A3 B-2800 Mechelen BE
- Agency: NICHOL, Maria
- Priority: US60/928,539 20070510; US60/931,844 20070525
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D209/46 ; A61K31/4985 ; A61P29/00
Abstract:
Novel fused pyrazine compounds are disclosed that have a formula represented by the following (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
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