发明申请
- 专利标题： N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF
- 专利标题（中）： N-苯基苯并噻吩酸衍生物及其用途
-
申请号： PCT/IL2008/001257申请日： 2008-09-18
-
公开(公告)号： WO2009037707A2公开(公告)日： 2009-03-26
- 发明人: ATTALI, Bernard , PERETZ, Asher
- 申请人： RAMOT AT TEL AVIV UNIVERSITY LTD. , ATTALI, Bernard , PERETZ, Asher
- 申请人地址： P.O. Box 39296 61392 Tel-aviv IL
- 专利权人： RAMOT AT TEL AVIV UNIVERSITY LTD.,ATTALI, Bernard,PERETZ, Asher
- 当前专利权人： RAMOT AT TEL AVIV UNIVERSITY LTD.,ATTALI, Bernard,PERETZ, Asher
- 当前专利权人地址： P.O. Box 39296 61392 Tel-aviv IL
- 代理机构： G.E. EHRLICH (1995) LTD. et al.
- 优先权： US60/960,215 20070920; US60/996,398 20071115
- 主分类号： C07C229/42
- IPC分类号： C07C229/42 ; C07C229/38 ; C07C237/34 ; C07C219/32 ; A61P9/10 ; A61P25/16 ; A61P25/28 ; A61K31/136
摘要：
ABSTRACT Compounds that can be used as openers or blockers of voltage-dependent potassium channels, and which are useful in the treatment of conditions such as central or peripheral nervous system disorders through the modulation of potassium ion flux through voltage-dependent potassium channels and/or depressing or enhancing cortical and/or peripheral neuron activity, compositions containing same and methods utilizing same are disclosed. Also disclosed are modulators of voltage-dependent potassium channels, which exhibit blocking of a TRPV1 channel, and hence are useful in the treatment of TRPV1-related conditions.
