发明申请
- 专利标题： BENZIMIDAZOLE COMPOUNDS
- 专利标题（中）： 苯并咪唑化合物
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申请号： PCT/US2008/087735申请日： 2008-12-19
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公开(公告)号： WO2009086138A1公开(公告)日： 2009-07-09
- 发明人: BERNOTAS, Ronald Charles , TRAVINS, Jeremy Mark , WROBEL, Jay E. , KAUFMAN, David Harry
- 申请人： WYETH , BERNOTAS, Ronald Charles , TRAVINS, Jeremy Mark , WROBEL, Jay E. , KAUFMAN, David Harry
- 申请人地址： 5 Giralda Farms Madison, New Jersey 07940 US
- 专利权人： WYETH,BERNOTAS, Ronald Charles,TRAVINS, Jeremy Mark,WROBEL, Jay E.,KAUFMAN, David Harry
- 当前专利权人： WYETH,BERNOTAS, Ronald Charles,TRAVINS, Jeremy Mark,WROBEL, Jay E.,KAUFMAN, David Harry
- 当前专利权人地址： 5 Giralda Farms Madison, New Jersey 07940 US
- 代理机构： NABINGER, Robert C. et al.
- 优先权： US61/016,070 20071221
- 主分类号： C07D235/06
- IPC分类号： C07D235/06 ; C07D235/08 ; C07D235/10 ; A61K31/4184 ; A61P3/00
摘要：
This invention relates generally to benzimidazole-based modulators of Liver X receptors (LXRs) and related methods (Formula I). wherein R 2 is C 6 -C 10 aryl or heteroaryl including 5-10 atoms, each of which is: (i) substituted with 1 R 7 , and (ii) optionally substituted with from 1-5 R e ; and R 1 , R 3 , R 4 , R 5 , R 6 , R 7 , and Re are defined herein.
