Invention Application
WO2009088876A3 TRANSGENIC NON-HUMAN ANIMALS EXPRESSING HUMAN BLOOD CLOTTING FACTORS
审中-公开
表达人血液粘稠因子的转基因非人动物
- Patent Title: TRANSGENIC NON-HUMAN ANIMALS EXPRESSING HUMAN BLOOD CLOTTING FACTORS
- Patent Title (中): 表达人血液粘稠因子的转基因非人动物
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Application No.: PCT/US2008088564Application Date: 2008-12-30
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Publication No.: WO2009088876A3Publication Date: 2009-12-03
- Inventor: SASGARY MARIA , SCHUSTER MARIA , SCHWARZ HANS-PETER , REIPERT BIRGIT , ANTOINE GERHARD , EHRLICH HARTMUT
- Applicant: BAXTER INT , BAXTER HEALTHCARE SA , SASGARY MARIA , SCHUSTER MARIA , SCHWARZ HANS-PETER , REIPERT BIRGIT , ANTOINE GERHARD , EHRLICH HARTMUT
- Assignee: BAXTER INT,BAXTER HEALTHCARE SA,SASGARY MARIA,SCHUSTER MARIA,SCHWARZ HANS-PETER,REIPERT BIRGIT,ANTOINE GERHARD,EHRLICH HARTMUT
- Current Assignee: BAXTER INT,BAXTER HEALTHCARE SA,SASGARY MARIA,SCHUSTER MARIA,SCHWARZ HANS-PETER,REIPERT BIRGIT,ANTOINE GERHARD,EHRLICH HARTMUT
- Priority: US1792007 2007-12-31
- Main IPC: C12N15/85
- IPC: C12N15/85 ; A01K67/027 ; A61K49/00 ; C07K14/745 ; C07K14/755 ; C12N9/64 ; G01N33/50
Abstract:
The present invention relates, in general, to development of non-human transgenic animals expressing a human blood clotting factor, such as Factor VIII, Factor VII, Factor IX and von Willebrand factor. The invention further provides methods of detecting immunogenic events against human blood clotting factor using the transgenic animals described.
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