Invention Application
- Patent Title: PD-1 BINDING PROTEINS
- Patent Title (中): PD-1结合蛋白
-
Application No.: PCT/US2009035825Application Date: 2009-03-03
-
Publication No.: WO2009114335A3Publication Date: 2010-06-03
- Inventor: FINNEFROCK ADAM C , FU TONG-MING , FREED DANIEL C , CASIMIRO DANILO R , LI FENGSHENG , TANG AIMIN
- Applicant: MERCK SHARP & DOHME , FINNEFROCK ADAM C , FU TONG-MING , FREED DANIEL C , CASIMIRO DANILO R , LI FENGSHENG , TANG AIMIN
- Assignee: MERCK SHARP & DOHME,FINNEFROCK ADAM C,FU TONG-MING,FREED DANIEL C,CASIMIRO DANILO R,LI FENGSHENG,TANG AIMIN
- Current Assignee: MERCK SHARP & DOHME,FINNEFROCK ADAM C,FU TONG-MING,FREED DANIEL C,CASIMIRO DANILO R,LI FENGSHENG,TANG AIMIN
- Priority: US6906008 2008-03-12
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C12P21/08
Abstract:
The present invention features PD-1 binding proteins, a subset of which inhibits binding of PD-L1 to the PD-1 receptor. These binding proteins can be employed to modulate the immune system through the manipulation of the PD-1 signaling pathway, enhancing host immunity to treat infections and cancer.
Information query
