Invention Application
WO2009118176A3 NOVEL 12 ALPHA-HYDROXYSTEROID DEHYDROGENASES, PRODUCTION AND USE THEREOF
审中-公开
新12ALPHA羟，生产和使用
- Patent Title: NOVEL 12 ALPHA-HYDROXYSTEROID DEHYDROGENASES, PRODUCTION AND USE THEREOF
- Patent Title (中): 新12ALPHA羟，生产和使用
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Application No.: PCT/EP2009002190Application Date: 2009-03-25
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Publication No.: WO2009118176A3Publication Date: 2010-01-07
- Inventor: AIGNER ARNO , GROSS RALF , SCHMID ROLF , BRAUN MICHAEL , MAUER STEFFEN
- Applicant: PHARMAZELL GMBH , AIGNER ARNO , GROSS RALF , SCHMID ROLF , BRAUN MICHAEL , MAUER STEFFEN
- Assignee: PHARMAZELL GMBH,AIGNER ARNO,GROSS RALF,SCHMID ROLF,BRAUN MICHAEL,MAUER STEFFEN
- Current Assignee: PHARMAZELL GMBH,AIGNER ARNO,GROSS RALF,SCHMID ROLF,BRAUN MICHAEL,MAUER STEFFEN
- Priority: EP08153330 2008-03-26
- Main IPC: C12N9/04
- IPC: C12N9/04
Abstract:
The invention relates to 12 a-hydroxysteroid dehydrogenases, nucleic acid sequences coding for the same, expression cassettes and vectors, recombinant microorganisms containing the corresponding coding nucleic acid sequences, a method for producing said 12 a-hydroxysteroid dehydrogenases, a method for enzymatic oxidation of 12 a-hydroxysteroids using said enzyme, a method for enzymatic reduction of 12-ketosteroids using said enzyme, a method for qualitative or quantitative determination of 12-ketosteroids and/or12a-hydroxysteroids using said 12a-hydroxysteroid dehydrogenases and a method for production of ursodesoxycholic acid, comprising the enzyme-catalysed cholic acid oxidation using said 12 a-hydroxysteroid dehydrogenases.
Public/Granted literature
- WO2009118176A8 NOVEL 12 ALPHA-HYDROXYSTEROID DEHYDROGENASES, PRODUCTION AND USE THEREOF Public/Granted day:2010-10-28
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