发明申请
WO2009124371A2 NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE
审中-公开
从TAURINE衍生的新化合物，其制备方法和含有这些化合物的药物组合物
- 专利标题： NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE
- 专利标题（中）： 从TAURINE衍生的新化合物，其制备方法和含有这些化合物的药物组合物
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申请号： PCT/BR2009000097申请日： 2009-04-09
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公开(公告)号： WO2009124371A2公开(公告)日： 2009-10-15
- 发明人: VIZIOLI EDNIR DE OLIVEIRA , CHIN CHUNG MAN , MENEGON RENATO FARINA , BLAU LORENA , SANTOS JEAN LEANDRO DOS , LONGO MARIA DO CARMO
- 申请人： EMS SA , UNIV ESTADUAL PAULISTA JULIO D , VIZIOLI EDNIR DE OLIVEIRA , CHIN CHUNG MAN , MENEGON RENATO FARINA , BLAU LORENA , SANTOS JEAN LEANDRO DOS , LONGO MARIA DO CARMO
- 专利权人： EMS SA,UNIV ESTADUAL PAULISTA JULIO D,VIZIOLI EDNIR DE OLIVEIRA,CHIN CHUNG MAN,MENEGON RENATO FARINA,BLAU LORENA,SANTOS JEAN LEANDRO DOS,LONGO MARIA DO CARMO
- 当前专利权人： EMS SA,UNIV ESTADUAL PAULISTA JULIO D,VIZIOLI EDNIR DE OLIVEIRA,CHIN CHUNG MAN,MENEGON RENATO FARINA,BLAU LORENA,SANTOS JEAN LEANDRO DOS,LONGO MARIA DO CARMO
- 优先权： BRPI0800951 2008-04-09
- 主分类号： C07C309/14
- IPC分类号： C07C309/14 ; A61K31/10
摘要：
The present invention relates to compounds derived from taurine with non-steroidal anti inflammatory activity. In a first embodiment, the present invention relates to compounds derived from taurine, in which taurine is bound directly by means of an amide bond or through an spacing group, to a compound selected from the group of non-steroidal anti inflammatory compounds, cited as derived from taurine presenting the Formula (I): in which R means the component with non-steroidal anti inflammatory activity. In a second embodiment, the invention provides a process for obtaining the compounds of Formula (I) by reaction of taurine with a compound belonging to the group of non-steroidal anti inflammatory (NSAIs), in order to obtain a compound derived from taurine by direct bond or through a spacing group of the taurine to the NSAI. The invention also relates to the pharmaceutical compositions comprising at least one compound derived from taurine presenting non-steroidal anti inflammatory activity.
公开/授权文献
