Invention Application
- Patent Title: OXAZOLIDINYL ANTIBIOTICS
- Patent Title (中): 恶唑烷基抗生素
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Application No.: PCT/IB2009054433Application Date: 2009-10-09
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Publication No.: WO2010041218A3Publication Date: 2010-10-14
- Inventor: HUBSCHWERLEN CHRISTIAN , RUEEDI GEORG , SURIVET JEAN-PHILIPPE , ZUMBRUNN ACKLIN CORNELIA
- Applicant: ACTELION PHARMACEUTICALS LTD , HUBSCHWERLEN CHRISTIAN , RUEEDI GEORG , SURIVET JEAN-PHILIPPE , ZUMBRUNN ACKLIN CORNELIA
- Assignee: ACTELION PHARMACEUTICALS LTD,HUBSCHWERLEN CHRISTIAN,RUEEDI GEORG,SURIVET JEAN-PHILIPPE,ZUMBRUNN ACKLIN CORNELIA
- Current Assignee: ACTELION PHARMACEUTICALS LTD,HUBSCHWERLEN CHRISTIAN,RUEEDI GEORG,SURIVET JEAN-PHILIPPE,ZUMBRUNN ACKLIN CORNELIA
- Priority: IB2008054175 2008-10-10
- Main IPC: C07D413/14
- IPC: C07D413/14 ; A61K31/4709 ; A61K31/498 ; A61K31/4985 ; A61K31/538 ; A61K31/5415 ; A61P31/04 ; C07D417/14 ; C07D471/04
Abstract:
The invention relates to antibacterial compounds of Formula (I) wherein R1 is alkoxy or halogen; U and V each independently are CH or N; "----" is a bond or is absent; W is CH or N or, when "----" is absent, W is CH2 or NH, with the proviso that U, V and W are not all N; A is a bond or CH2; R2 is H or, provided A is CH2, may also be OH; m and n each independently are 0 or 1; D is CH2 or a bond; G represents a phenyl group substituted once or twice in the meta and/or para position (s) by substituents selected from alkyl, (C1-C3)alkyl and halogen, or G is a group G1 or G2 wherein Z1, Z2 and Z3 may each represent CH or N; X is N or CH and Q is O or S; it being understood that if m and n each are 0, then A is CH2; and salts of such compounds.
Information query