Invention Application
- Patent Title: GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUT COME PREDICTION IN PEDEATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA
- Patent Title (中): 基因表达分类器用于免疫存活和极少残留疾病改善危险分层和输出预后的急性淋巴细胞白血病
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Application No.: PCT/US2009006117Application Date: 2009-11-16
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Publication No.: WO2010056351A3Publication Date: 2010-11-18
- Inventor: WILLMAN CHERYL L , HARVEY RICHARD , KANG HUINING , BEDRICK EDWARD , WANG XUEFEI , ATLAS SUSAN , CHEN I-MING
- Applicant: STC UNM , WILLMAN CHERYL L , HARVEY RICHARD , KANG HUINING , BEDRICK EDWARD , WANG XUEFEI , ATLAS SUSAN , CHEN I-MING
- Assignee: STC UNM,WILLMAN CHERYL L,HARVEY RICHARD,KANG HUINING,BEDRICK EDWARD,WANG XUEFEI,ATLAS SUSAN,CHEN I-MING
- Current Assignee: STC UNM,WILLMAN CHERYL L,HARVEY RICHARD,KANG HUINING,BEDRICK EDWARD,WANG XUEFEI,ATLAS SUSAN,CHEN I-MING
- Priority: US27928109 2009-10-16; US19934208 2008-11-14
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12N15/12
Abstract:
The present invention relates to the identification of genetic markers patients with leukemia, especially including acute lymphoblastic leukemia (ALL) at high risk for relapse, especially high risk B-precursor acute lymphoblastic leukemia (B-ALL) and associated methods and their relationship to therapeutic outcome. The present invention also relates to diagnostic, prognostic and related methods using these genetic markers, as well as kits which provide microchips and/or immunoreagents for performing analysis on leukemia patients.
Information query
