Invention Application
WO2010093890A3 PROCESSES FOR PRODUCING PHENYL-6-(1-(PHENYL)UREIDO)NICOTINAMIDES
审中-公开
生产苯基-6-（1-（苯基）尿嘧啶）的方法NICOTINAMIDES
- Patent Title: PROCESSES FOR PRODUCING PHENYL-6-(1-(PHENYL)UREIDO)NICOTINAMIDES
- Patent Title (中): 生产苯基-6-（1-（苯基）尿嘧啶）的方法NICOTINAMIDES
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Application No.: PCT/US2010024054Application Date: 2010-02-12
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Publication No.: WO2010093890A3Publication Date: 2010-12-16
- Inventor: ROEPER STEFANIE , LOOKER ADAM R , MARTINOT THEODORE A , NEUBERT-LANGILLE BOBBIANNA , RYAN MICHAEL P , SNOONIAN JOHN R
- Applicant: VERTEX PHARMA , ROEPER STEFANIE , LOOKER ADAM R , MARTINOT THEODORE A , NEUBERT-LANGILLE BOBBIANNA , RYAN MICHAEL P , SNOONIAN JOHN R
- Assignee: VERTEX PHARMA,ROEPER STEFANIE,LOOKER ADAM R,MARTINOT THEODORE A,NEUBERT-LANGILLE BOBBIANNA,RYAN MICHAEL P,SNOONIAN JOHN R
- Current Assignee: VERTEX PHARMA,ROEPER STEFANIE,LOOKER ADAM R,MARTINOT THEODORE A,NEUBERT-LANGILLE BOBBIANNA,RYAN MICHAEL P,SNOONIAN JOHN R
- Priority: US15265309 2009-02-13
- Main IPC: C07D213/80
- IPC: C07D213/80 ; A61K31/4418 ; A61P29/00 ; A61P37/06 ; C07D213/803
Abstract:
The present invention relates to processes for the preparation of compounds useful as inhibitors of p38 kinase. The processes of the present invention are amenable for large scale preparation and produce stable phenyl-6-(1-(phenyl)ureido)nicotinamides in high purity and yields.
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