Invention Application
- Patent Title: MICROFLUIDIC DEVICE AND RELATED METHODS
- Patent Title (中): 微流体装置及相关方法
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Application No.: PCT/US2010/024076Application Date: 2010-02-12
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Publication No.: WO2010101708A2Publication Date: 2010-09-10
- Inventor: COLLINS, Scott, D. , SMITH, Rosemary, L. , HOCK, Janet, M.
- Applicant: UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEES , MAINE INSTITUTE FOR HUMAN GENETICS AND HEALTH, INC. , COLLINS, Scott, D. , SMITH, Rosemary, L. , HOCK, Janet, M.
- Applicant Address: 107 Maine Avenue Bangor, ME 04401 US
- Assignee: UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEES,MAINE INSTITUTE FOR HUMAN GENETICS AND HEALTH, INC.,COLLINS, Scott, D.,SMITH, Rosemary, L.,HOCK, Janet, M.
- Current Assignee: UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEES,MAINE INSTITUTE FOR HUMAN GENETICS AND HEALTH, INC.,COLLINS, Scott, D.,SMITH, Rosemary, L.,HOCK, Janet, M.
- Current Assignee Address: 107 Maine Avenue Bangor, ME 04401 US
- Agency: GILLESPIE, Ted, C.
- Priority: US61/157,439 20090304
- Main IPC: G01N35/08
- IPC: G01N35/08 ; G01N33/53 ; C12Q1/04 ; C12Q1/70
Abstract:
A combinatorial microenvironment generator is configured for the generation of arbitrary, user-defined, steady-state, concentration gradients with negligible to no flow through the growth medium to perturb diffusion gradients or cellular growth. More importantly, the absolute concentrations and/or gradients can be dynamically altered upon request both spatially and temporally to impose tailored concentration fields for in-situ stimulus studies. Here, diffusion occurs via an array of ports, each of which can be an independently controlled source/sink. Together, the array of ports establishes a user-defined, 3D concentration profile. Useful methods related to this device are also provided.
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