Invention Application
WO2010146604A8 PROCESSES FOR PREPARING METFORMIN HYDROCHLORIDE 审中-公开
制备羟基氯化氢的方法

PROCESSES FOR PREPARING METFORMIN HYDROCHLORIDE
Abstract:
A process for reducing dimethylamine content in metformin hydrochloride is disclosed. The process comprises: (a) providing metformin hydrochloride having dimethylamine content more than 15 ppm; (b) pulverizing the metformin hydrochloride; (c) slurrying the metformin hydrochloride in one or more Cj-C4 alcohol solvents; and (d) isolating the metformin hydrochloride.
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