- 专利标题： N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS
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申请号： PCT/US2010/001926申请日： 2010-07-08
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公开(公告)号： WO2011005322A3公开(公告)日： 2011-01-13
- 发明人: CESATI, Richard, R. , HARRIS, Thomas, D. , ROBINSON, Simon, P. , LOOBY, Richard, J. , CHEESMAN, Edward, H. , YALAMANCHILI, Padmaja , CASEBIER, David, S.
- 申请人： LANTHEUS MEDICAL IMAGING, INC. , CESATI, Richard, R. , HARRIS, Thomas, D. , ROBINSON, Simon, P. , LOOBY, Richard, J. , CHEESMAN, Edward, H. , YALAMANCHILI, Padmaja , CASEBIER, David, S.
- 申请人地址： 331 Treble Cove Road North Billerica, MA 01862 US
- 专利权人： LANTHEUS MEDICAL IMAGING, INC.,CESATI, Richard, R.,HARRIS, Thomas, D.,ROBINSON, Simon, P.,LOOBY, Richard, J.,CHEESMAN, Edward, H.,YALAMANCHILI, Padmaja,CASEBIER, David, S.
- 当前专利权人： LANTHEUS MEDICAL IMAGING, INC.,CESATI, Richard, R.,HARRIS, Thomas, D.,ROBINSON, Simon, P.,LOOBY, Richard, J.,CHEESMAN, Edward, H.,YALAMANCHILI, Padmaja,CASEBIER, David, S.
- 当前专利权人地址： 331 Treble Cove Road North Billerica, MA 01862 US
- 代理机构： ANDERSON, MaryDilys, S.
- 优先权： US61/223,946 20090708
- 主分类号： C07C271/22
- IPC分类号： C07C271/22 ; C07D257/02 ; A61K49/10
摘要：
The present disclosure is directed to compounds, diagnostic agents, and related methods. In some cases, methods for treating patients are provided. More specifically, the disclosure provides compounds, diagnostic agents, and kits for detecting and/or imaging and/or monitoring elastin rich tissues. In addition, the disclosure provides methods of detecting and/or imaging and/or monitoring the presence of coronary plaque, carotid plaque, iliac/femoral plaque, aortic plaque, renal artery plaque, plaque of any arterial vessel, aneurism, vasculitis, other diseases of the arterial wall, and/or damage or structural changes in ligaments, uterus, lungs or skin, as indicated by changes in total vessel wall area, internal lumen size, and exterior arterial perimeter.
