Invention Application
- Patent Title: ALPHA-FETOPROTEIN 'RING AND TAIL' PEPTIDES
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Application No.: PCT/US2011/021560Application Date: 2011-01-18
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Publication No.: WO2011088462A3Publication Date: 2011-07-21
- Inventor: ANDERSEN, Thomas, T. , JACOBSON, Herbert I. , BENNETT, James A. , JOSEPH, Leroy , BRYAN, Alberto
- Applicant: ALBANY MEDICAL COLLEGE , ANDERSEN, Thomas, T. , JACOBSON, Herbert I. , BENNETT, James A. , JOSEPH, Leroy , BRYAN, Alberto
- Applicant Address: 47 New Scotland Avenue Albany, New York 12203 US
- Assignee: ALBANY MEDICAL COLLEGE,ANDERSEN, Thomas, T.,JACOBSON, Herbert I.,BENNETT, James A.,JOSEPH, Leroy,BRYAN, Alberto
- Current Assignee: ALBANY MEDICAL COLLEGE,ANDERSEN, Thomas, T.,JACOBSON, Herbert I.,BENNETT, James A.,JOSEPH, Leroy,BRYAN, Alberto
- Current Assignee Address: 47 New Scotland Avenue Albany, New York 12203 US
- Agency: DIAS, Kathy Smith
- Priority: US61/295,897 20100118
- Main IPC: C07K7/52
- IPC: C07K7/52 ; A61K38/12 ; A61P35/00
Abstract:
The invention relates to compounds that are analogs of a cyclic peptide, cyclo [EKTOVNOGN], AFPep, that has anti-estrotrophic activity. The analogs of the invention include peptides and petidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.
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