发明申请
WO2011097572A1 TRANSCRIPTIONAL PROFILING AND BIOMARKER-BASED METHODS FOR IDENTIFYING AND EVALUATING AGENTS FOR ANTIOXIDANT EFFICACY IN COSMETIC SKIN CARE FORMULATIONS
审中-公开
用于识别和评估化妆品护肤产品中抗氧化剂效力的代谢分析和基于生物标记的方法
- 专利标题： TRANSCRIPTIONAL PROFILING AND BIOMARKER-BASED METHODS FOR IDENTIFYING AND EVALUATING AGENTS FOR ANTIOXIDANT EFFICACY IN COSMETIC SKIN CARE FORMULATIONS
- 专利标题（中）： 用于识别和评估化妆品护肤产品中抗氧化剂效力的代谢分析和基于生物标记的方法
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申请号： PCT/US2011/023918申请日： 2011-02-07
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公开(公告)号： WO2011097572A1公开(公告)日： 2011-08-11
- 发明人: FINLAY, Deborah, Ruth , BINDER, Robert, Lloyd , ROBINSON, Michael, Keith , OSBORNE, Rosemarie , MULLINS, Lisa, Ann
- 申请人： THE PROCTER & GAMBLE COMPANY , FINLAY, Deborah, Ruth , BINDER, Robert, Lloyd , ROBINSON, Michael, Keith , OSBORNE, Rosemarie , MULLINS, Lisa, Ann
- 申请人地址： One Procter & Gamble Plaza Cincinnati, OH 45202 US
- 专利权人： THE PROCTER & GAMBLE COMPANY,FINLAY, Deborah, Ruth,BINDER, Robert, Lloyd,ROBINSON, Michael, Keith,OSBORNE, Rosemarie,MULLINS, Lisa, Ann
- 当前专利权人： THE PROCTER & GAMBLE COMPANY,FINLAY, Deborah, Ruth,BINDER, Robert, Lloyd,ROBINSON, Michael, Keith,OSBORNE, Rosemarie,MULLINS, Lisa, Ann
- 当前专利权人地址： One Procter & Gamble Plaza Cincinnati, OH 45202 US
- 代理机构： EVERETT, Denise, M. et al.
- 优先权： US61/301,758 20100205
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Gene panels, microarrays and biomarker panels relating to genes and gene products associated with age-related oxidative damage to skin, and transcriptional profiling-based methods for identification and evaluation of cosmetic agents for prevention, reversal, or reduction of oxidative damage to skin. Cosmetic agents and compositions comprising the cosmetic agents, capable of inducing nrf2-mediated activation of the antioxidant response element to increase expression of Phase 2 enzymes, methods for restoring optimal redox status to skin employing the agents, and methods for identifying and evaluating cosmetic agents acting via the nrf2-mediated mechanism.
