发明申请
WO2011100131A9 MONOMERS AND OLIGONUCLEOTIDES COMPRISING CYCLOADDITION ADDUCT(S)
审中-公开
包含环加成反应的单体和寡核苷酸（S）
- 专利标题： MONOMERS AND OLIGONUCLEOTIDES COMPRISING CYCLOADDITION ADDUCT(S)
- 专利标题（中）： 包含环加成反应的单体和寡核苷酸（S）
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申请号： PCT/US2011022975申请日： 2011-01-28
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公开(公告)号： WO2011100131A9公开(公告)日： 2011-10-20
- 发明人: MANOHARAN MUTHIAH , JAYAPRAKASH NARAYANANNAIR K , RAJEEV KALLANTHOTTAHIL G , JUNG MICHAEL E
- 申请人： ALNYLAM PHARMACUTICALS INC , MANOHARAN MUTHIAH , JAYAPRAKASH NARAYANANNAIR K , RAJEEV KALLANTHOTTAHIL G , JUNG MICHAEL E
- 专利权人： ALNYLAM PHARMACUTICALS INC,MANOHARAN MUTHIAH,JAYAPRAKASH NARAYANANNAIR K,RAJEEV KALLANTHOTTAHIL G,JUNG MICHAEL E
- 当前专利权人： ALNYLAM PHARMACUTICALS INC,MANOHARAN MUTHIAH,JAYAPRAKASH NARAYANANNAIR K,RAJEEV KALLANTHOTTAHIL G,JUNG MICHAEL E
- 优先权： US29929610 2010-01-28; US40598010 2010-10-22
- 主分类号： A61K47/48
- IPC分类号： A61K47/48 ; C07D249/04 ; C07H5/04
摘要：
The invention features compounds of formula (V) or( XII). In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodeficiencies and immunosuppression.
公开/授权文献
