Invention Application
- Patent Title: N- SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE - GATED SODIUM CHANNELS
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Application No.: PCT/IB2011/052940Application Date: 2011-07-04
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Publication No.: WO2012007868A3Publication Date: 2012-01-19
- Inventor: BROWN, Alan, Daniel , RAWSON, David, James , STORER, Robert, Ian , SWAIN, Nigel, Alan
- Applicant: PFIZER LIMITED , BROWN, Alan, Daniel , RAWSON, David, James , STORER, Robert, Ian , SWAIN, Nigel, Alan
- Applicant Address: Ramsgate Road Sandwich Kent CT13 9NJ GB
- Assignee: PFIZER LIMITED,BROWN, Alan, Daniel,RAWSON, David, James,STORER, Robert, Ian,SWAIN, Nigel, Alan
- Current Assignee: PFIZER LIMITED,BROWN, Alan, Daniel,RAWSON, David, James,STORER, Robert, Ian,SWAIN, Nigel, Alan
- Current Assignee Address: Ramsgate Road Sandwich Kent CT13 9NJ GB
- Priority: US61/484,838 20110511; US61/363,371 20100712
- Main IPC: C07C311/51
- IPC: C07C311/51 ; A61K31/18 ; A61P25/04
Abstract:
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein X, Ar 1 , R 1 , R 2 , R 3 , R 4 and R 5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
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