发明申请
- 专利标题： SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF
- 专利标题（中）： 取代的羟基酸及其用途
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申请号： PCT/US2011/044340申请日： 2011-07-18
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公开(公告)号： WO2012012320A1公开(公告)日： 2012-01-26
- 发明人: CALDERWOOD, Emily, F. , ENGLAND, Dylan, B. , GOULD, Alexandra, E. , HARRISON, Sean, J. , MA, Liting
- 申请人： MILLENIUM PHARMACEUTICALS, INC. , CALDERWOOD, Emily, F. , ENGLAND, Dylan, B. , GOULD, Alexandra, E. , HARRISON, Sean, J. , MA, Liting
- 申请人地址： 40 Landsdowne Street Cambridge, MA 02139 US
- 专利权人： MILLENIUM PHARMACEUTICALS, INC.,CALDERWOOD, Emily, F.,ENGLAND, Dylan, B.,GOULD, Alexandra, E.,HARRISON, Sean, J.,MA, Liting
- 当前专利权人： MILLENIUM PHARMACEUTICALS, INC.,CALDERWOOD, Emily, F.,ENGLAND, Dylan, B.,GOULD, Alexandra, E.,HARRISON, Sean, J.,MA, Liting
- 当前专利权人地址： 40 Landsdowne Street Cambridge, MA 02139 US
- 代理机构： KLUNDER, Janice M. et al.
- 优先权： US61/365,524 20100719; US61/426,243 20101222
- 主分类号： C07C259/04
- IPC分类号： C07C259/04
摘要：
This invention provides compounds of formula (I): wherein R 1a , R 1b , R 1c , R 2a , R 2b , R 2c and R 2d have values as described in the specification, useful as inhibitors of HDAC6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders.
