发明申请
- 专利标题： VACCINE COMPOSITION COMPRISING COMPLEXED IMMUNOSTIMULATORY NUCLEIC ACIDS AND ANTIGENS PACKAGED WITH DISULFIDE-LINKED POLYETHYLENEGLYCOL/PEPTIDE CONJUGATES
- 专利标题（中）： 包含复合免疫细胞核酸的疫苗组合物和用分离的聚乙二醇/肽结合物包装的抗体
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申请号： PCT/EP2011/000827申请日： 2011-02-21
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公开(公告)号： WO2012113413A1公开(公告)日： 2012-08-30
- 发明人: BAUMHOF, Patrick , KALLEN, Karl-Josef , FOTIN-MLECZEK, Mariola
- 申请人： CUREVAC GMBH , BAUMHOF, Patrick , KALLEN, Karl-Josef , FOTIN-MLECZEK, Mariola
- 申请人地址： Paul-Ehrlich-Str. 15 72076 Tübingen DE
- 专利权人： CUREVAC GMBH,BAUMHOF, Patrick,KALLEN, Karl-Josef,FOTIN-MLECZEK, Mariola
- 当前专利权人： CUREVAC GMBH,BAUMHOF, Patrick,KALLEN, Karl-Josef,FOTIN-MLECZEK, Mariola
- 当前专利权人地址： Paul-Ehrlich-Str. 15 72076 Tübingen DE
- 代理机构： GRAF VON STOSCH, Andreas et al.
- 主分类号： A61K47/48
- IPC分类号： A61K47/48
摘要：
The present invention is directed to a composition or vaccine composition comprising a) an adjuvant component comprising or consisting of at least one immunostimulatory nucleic acid sequence, complexed with a complexing agent; b) an antigen, preferably a protein or peptide antigen and/or a nucleic acid sequence encoding said antigen; and c) a carrier molecule for combined packaging the adjuvant component and the antigen. The present invention is also directed to the first medical use of such a composition or vaccine composition and to the second medical use of such a composition or vaccine composition or components thereof for the treatment of diseases, such as infectious or cancer or tumour diseases as defined herein. The present invention furthermore discloses kits comprising such a composition or vaccine composition.
