Invention Application
- Patent Title: METHODS FOR LUNG CANCER CLASIFICATION
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Application No.: PCT/IL2012/000131Application Date: 2012-03-26
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Publication No.: WO2012131670A3Publication Date: 2012-10-04
- Inventor: LITHWICK YANAI, Gila , BENJAMIN, Hila
- Applicant: ROSETTA GENOMICS LTD , LITHWICK YANAI, Gila , BENJAMIN, Hila
- Applicant Address: 10 Plaut St. 76706 Rehovot IL
- Assignee: ROSETTA GENOMICS LTD,LITHWICK YANAI, Gila,BENJAMIN, Hila
- Current Assignee: ROSETTA GENOMICS LTD,LITHWICK YANAI, Gila,BENJAMIN, Hila
- Current Assignee Address: 10 Plaut St. 76706 Rehovot IL
- Agency: DR. EYAL BRESSLER LTD
- Priority: US61/468,077 20110328
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention provides specific nucleic acid sequences for use in the identification, classification and diagnosis of various sub-types of lung cancers. The present invention permits one to accurately classify lung cancers based on their miR expression profile without further manipulation. Using microRNA microarray data generated from over two hundred formalin-fixed paraffin-embedded (FFPE) resection samples, fine needle aspiration (FNA) samples and fine needle biopsy (FNB) samples of primary lung cancer, microRNA expression profiles were identified that differ significantly for various sub-types of lung cancer.
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