Invention Application
- Patent Title: SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
- Patent Title (中): 取代的二氨基酰胺和二氨基嘌呤嘧啶，其组合物及其处理方法
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Application No.: PCT/US2012/034349Application Date: 2012-04-20
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Publication No.: WO2012145569A1Publication Date: 2012-10-26
- Inventor: BENNETT, Brydon, L. , ELSNER, Jan , ERDMAN, Paul , HILGRAF, Robert , LEBRUN, Laurie, Ann , MCCARRICK, Meg , MOGHADDAM, Mehran, F. , NAGY, Mark, A. , NORRIS, Stephen , PAISNER, David, A. , SLOSS, Marianne , ROMANOW, William, J. , SATOH, Yoshitaka , TIKHE, Jayashree , YOON, Won, Hyung , DELGADO, Mercedes
- Applicant: SIGNAL PHARMACEUTICALS, LLC , BENNETT, Brydon, L. , ELSNER, Jan , ERDMAN, Paul , HILGRAF, Robert , LEBRUN, Laurie, Ann , MCCARRICK, Meg , MOGHADDAM, Mehran, F. , NAGY, Mark, A. , NORRIS, Stephen , PAISNER, David, A. , SLOSS, Marianne , ROMANOW, William, J. , SATOH, Yoshitaka , TIKHE, Jayashree , YOON, Won, Hyung , DELGADO, Mercedes
- Applicant Address: 4550 Towne Centre Court San Diego, CA 92121 US
- Assignee: SIGNAL PHARMACEUTICALS, LLC,BENNETT, Brydon, L.,ELSNER, Jan,ERDMAN, Paul,HILGRAF, Robert,LEBRUN, Laurie, Ann,MCCARRICK, Meg,MOGHADDAM, Mehran, F.,NAGY, Mark, A.,NORRIS, Stephen,PAISNER, David, A.,SLOSS, Marianne,ROMANOW, William, J.,SATOH, Yoshitaka,TIKHE, Jayashree,YOON, Won, Hyung,DELGADO, Mercedes
- Current Assignee: SIGNAL PHARMACEUTICALS, LLC,BENNETT, Brydon, L.,ELSNER, Jan,ERDMAN, Paul,HILGRAF, Robert,LEBRUN, Laurie, Ann,MCCARRICK, Meg,MOGHADDAM, Mehran, F.,NAGY, Mark, A.,NORRIS, Stephen,PAISNER, David, A.,SLOSS, Marianne,ROMANOW, William, J.,SATOH, Yoshitaka,TIKHE, Jayashree,YOON, Won, Hyung,DELGADO, Mercedes
- Current Assignee Address: 4550 Towne Centre Court San Diego, CA 92121 US
- Agency: INSOGNA, Anthony M. et al.
- Priority: US61/555,339 20111103; US61/478,076 20110422
- Main IPC: C07D239/48
- IPC: C07D239/48 ; C07D405/02 ; C07D401/12 ; C07D409/12
Abstract:
Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R 1 , R 2 , R 3, and R 4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.
Information query
