Invention Application
- Patent Title: ANTI-ERBB3 ANTIBODIES AND USES THEREOF
- Patent Title (中): 抗ERBB3抗体及其用途
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Application No.: PCT/US2012/056446Application Date: 2012-09-21
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Publication No.: WO2013048883A2Publication Date: 2013-04-04
- Inventor: DALY, Christopher , MACDONALD, Douglas , DUAN, Xunbao
- Applicant: REGENERON PHARMACEUTICALS, INC.
- Applicant Address: 777 Old Saw Mill River Road Tarrytown, NY 10591 US
- Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee Address: 777 Old Saw Mill River Road Tarrytown, NY 10591 US
- Agency: COTTINGHAM, Frank
- Priority: US61/614,565 20120323; US61/557,460 20111109; US61/541,312 20110930
- Main IPC: C07K16/32
- IPC: C07K16/32 ; A61K39/395
Abstract:
The present invention provides antibodies that bind to ErbB3 and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human ErbB3. In certain embodiments, the antibodies of the present invention block the interaction of ErbB3 with an ErbB3 ligand such as neuregulin 1. The antibodies of the invention are useful for the treatment of various cancers.
Information query
