Invention Application
- Patent Title: ANTI-HUMAN SEMA4A ANTIBODIES USEFUL TO TREAT DISEASE
- Patent Title (中): 抗人类SEMA4A抗体有助于治疗疾病
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Application No.: PCT/US2012/058910Application Date: 2012-10-05
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Publication No.: WO2013052772A2Publication Date: 2013-04-11
- Inventor: LIU, Yong-jun , LU, Ning , BOVER, Laura , TSURUSHITA, Naoya , TSO, J., Yun , KUMAR, Shankar
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: 201 West 7th Street Austin, TX 78701 US
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: 201 West 7th Street Austin, TX 78701 US
- Agency: PARKER, David L.
- Priority: US61/543,877 20111006
- Main IPC: C07K16/18
- IPC: C07K16/18 ; A61K39/395 ; A61P35/00 ; A61P37/08
Abstract:
Anti-human sema4A antibodies useful in treating autoimmune diseases, cancers and other disease are provided herein. Anti-human sema4A antibodies can inhibit T cell proliferation and Th2 differentiation induced by IL-4, anti-CD3, anti-CD28 and recombinant sema4A.
Information query
