发明申请
WO2013055177A1 COMPOSITE FORMULATION COMPRISING A TABLET ENCAPSULATED IN A HARD CAPSULE
审中-公开
包含硬化胶囊中的片剂的复合制剂
- 专利标题: COMPOSITE FORMULATION COMPRISING A TABLET ENCAPSULATED IN A HARD CAPSULE
- 专利标题(中): 包含硬化胶囊中的片剂的复合制剂
-
申请号: PCT/KR2012/008380申请日: 2012-10-15
-
公开(公告)号: WO2013055177A1公开(公告)日: 2013-04-18
- 发明人: KIM, Kyeong Soo , JANG, Ki Young , PARK, Seung Jae , KIM, Yong Il , PARK, Jae Hyun , WOO, Jong Soo
- 申请人: HANMI PHARM CO., LTD.
- 申请人地址: #893-5, Hajeo-ri, Paltan-myeon, Hwaseong-si, 445-910 KR
- 专利权人: HANMI PHARM CO., LTD.
- 当前专利权人: HANMI PHARM CO., LTD.
- 当前专利权人地址: #893-5, Hajeo-ri, Paltan-myeon, Hwaseong-si, 445-910 KR
- 代理机构: FIRSTLAW P.C.
- 优先权: KR10-2011-0104374 20111013
- 主分类号: A61K9/48
- IPC分类号: A61K9/48 ; A61K9/20 ; A61K9/54 ; A61K9/52
摘要:
The present invention relates to a hard capsule composite formulation comprising a capsule having a hemispherical closure at each end and an interior space; and one or more tablets encapsulated in the capsule, wherein the tablet or the tablets as a whole have a shape conforming to the internal space of the capsule. The hard capsule composite formulation can efficiently charge pharmaceutical compositions inside the limited interior space of the capsule, and hence, it allows packing a high-dose of pharmaceutical composition in a relatively small-sized capsule, which increases productivity and patient compliance. Also, the composite formulation exhibits good dissolution rate because pharmaceutically active ingredients contained in the capsule are separated from one another, and thus, the ingredients are less affected by the dissolution rate of one another, allowing good storage stability which can optimize the therapeutic effects.