Invention Application
WO2013075823A1 TRANSDERMAL THERAPEUTIC SYSTEM COMPRISING ROTIGOTINE AND CRYSTALLIZATION INHIBITOR
审中-公开
包含ROTIGOTINE和结晶抑制剂的透皮治疗系统
- Patent Title: TRANSDERMAL THERAPEUTIC SYSTEM COMPRISING ROTIGOTINE AND CRYSTALLIZATION INHIBITOR
- Patent Title (中): 包含ROTIGOTINE和结晶抑制剂的透皮治疗系统
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Application No.: PCT/EP2012/004818Application Date: 2012-11-21
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Publication No.: WO2013075823A1Publication Date: 2013-05-30
- Inventor: SAHR, Florian , LANG, Susanne , RYBACH, Simon , FITZNER, Ansgar
- Applicant: ALFRED E. TIEFENBACHER (GMBH & CO. KG) , AMW GMBH
- Applicant Address: Van-der-Smissen-Str. 1 22767 Hamburg DE
- Assignee: ALFRED E. TIEFENBACHER (GMBH & CO. KG),AMW GMBH
- Current Assignee: ALFRED E. TIEFENBACHER (GMBH & CO. KG),AMW GMBH
- Current Assignee Address: Van-der-Smissen-Str. 1 22767 Hamburg DE
- Agency: FELDMANN, Ute
- Priority: DE10 20111122; US61/667,528 20120703; US61/667,507 20120703; DE10 20120703; DE10 20120703
- Main IPC: A61K31/381
- IPC: A61K31/381 ; A61K9/70 ; A61P25/16 ; A61P25/14 ; A61P25/28
Abstract:
The present invention relates to an inventive transdermal therapeutic system (TTS) comprising rotigotine, a pharmaceutically acceptable adhesive comprising styrene butadiene block copolymer and a crystallization inhibitor, an inventive matrix with an extended release of rotigotine suitable for a transdermal therapeutic system, an inventive production method of a respective matrix or a respective TTS comprising rotigotine, as well as uses of the inventive matrix and the inventive TTS.
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