Example doors having a seal attached to an edge member of a door panel are disclosed herein. An example seal includes a flexible sheet of material with its longitudinal edges turned inward toward a more central portion of the sheet such that the sheet is turned partially or somewhat inside-out to provide a bulging seal geometry that is favorable for sealing in multiple directions. The seal, for example, is suitable for sealing in a head-on direction engaging an abutting surface, such as a doorjamb. The seal can also seal in sliding engagement with an adjacent surface parallel to the door panel. In some examples, the sheet defines a hollow chamber in which the longitudinal edges of the sheet reinforce or brace an exterior curved portion of the seal. In some examples, the sheet of material is a unitary seamless piece with an attached touch-and-hold fastener that makes the seal readily replaceable.