Invention Application
WO2013148768A1 CRYSTALLINE FORMS OF (R)-3-[N-(3'-CHLOROBIPHENYL-4-YLMETHYL)-N'-(3-HYDROXYISOXAZOLE-5-CARBONYL)HYDRAZINO]-2-HYDROXYPROPIONIC ACID ISOPROPYL ESTER
审中-公开
（R）-3- [N-（3'-氯代苄基）-4-甲基乙基）-N' - （3-羟基氧代唑-5-基）乙酰肼] -2-羟基丙酸异丙酯的晶体形式
- Patent Title: CRYSTALLINE FORMS OF (R)-3-[N-(3'-CHLOROBIPHENYL-4-YLMETHYL)-N'-(3-HYDROXYISOXAZOLE-5-CARBONYL)HYDRAZINO]-2-HYDROXYPROPIONIC ACID ISOPROPYL ESTER
- Patent Title (中): （R）-3- [N-（3'-氯代苄基）-4-甲基乙基）-N' - （3-羟基氧代唑-5-基）乙酰肼] -2-羟基丙酸异丙酯的晶体形式
-
Application No.: PCT/US2013/034005Application Date: 2013-03-27
-
Publication No.: WO2013148768A1Publication Date: 2013-10-03
- Inventor: THALLADI, Venkat, R. , NZEREM, Jerry , RAPTA, Miroslav
- Applicant: THERAVANCE, INC. , THALLADI, Venkat, R. , NZEREM, Jerry , RAPTA, Miroslav
- Applicant Address: 901 Gateway Boulevard South San Francisco, CA 94080 US
- Assignee: THERAVANCE, INC.,THALLADI, Venkat, R.,NZEREM, Jerry,RAPTA, Miroslav
- Current Assignee: THERAVANCE, INC.,THALLADI, Venkat, R.,NZEREM, Jerry,RAPTA, Miroslav
- Current Assignee Address: 901 Gateway Boulevard South San Francisco, CA 94080 US
- Agency: HAGENAH, Jeffrey, A. et al.
- Priority: US61/616,785 20120328
- Main IPC: C07D261/18
- IPC: C07D261/18 ; A61K31/42 ; A61P9/00
Abstract:
The invention provides crystalline forms of (R)-3-[N-(3'- chlorobiphenyl-4-ylmethyl)-N'-(3-hydroxyisoxazole-5-carbonyl) hydrazino]-2-hydroxypropionic acid isopropyl ester. The application also provides pharmaceutical compositions comprising the crystalline compound and processes and intermediates for preparing the crystalline compound and methods of using the crystalline compound to treat diseases.
Information query
