发明申请
WO2013152039A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS
审中-公开
化合物，组合物和调节性溃疡和治疗激素性疾病的方法
- 专利标题： COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS
- 专利标题（中）： 化合物，组合物和调节性溃疡和治疗激素性疾病的方法
-
申请号： PCT/US2013/035021申请日： 2013-04-02
-
公开(公告)号： WO2013152039A1公开(公告)日： 2013-10-10
- 发明人: STOCKWELL, Brent, R. , DIXON, Scott, J. , SKOUTA, Rachid
- 申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , STOCKWELL, Brent, R. , DIXON, Scott, J. , SKOUTA, Rachid
- 申请人地址： Office of the General Counsel 412 Low Library, Mail Code 4308 535 West 116th Street New York, NY 10027 US
- 专利权人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,STOCKWELL, Brent, R.,DIXON, Scott, J.,SKOUTA, Rachid
- 当前专利权人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,STOCKWELL, Brent, R.,DIXON, Scott, J.,SKOUTA, Rachid
- 当前专利权人地址： Office of the General Counsel 412 Low Library, Mail Code 4308 535 West 116th Street New York, NY 10027 US
- 代理机构： HOOPER, Kevin, C.
- 优先权： US61/619,315 20120402
- 主分类号： A61K31/245
- IPC分类号： A61K31/245
摘要：
The present invention provides, inter alia, a compound having the structure: (Formula (I). Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for treating or ameliorating the effects of an excitotoxic disorder in a subject, methods of modulating ferroptosis in a subject, methods of reducing reactive oxygen species (ROS) in a cell, and methods for treating or ameliorating the effects of a neurodegenerative disease.
IPC分类:
