发明申请
WO2013166378A1 HYDRODYNAMIC METHODS FOR DELIVERING FLUIDS TO KIDNEY TISSUES AND RELATED MATERIALS AND METHODS
审中-公开
用于将流体输送到KIDNEY组织的水动力学方法及相关材料和方法
- 专利标题: HYDRODYNAMIC METHODS FOR DELIVERING FLUIDS TO KIDNEY TISSUES AND RELATED MATERIALS AND METHODS
- 专利标题(中): 用于将流体输送到KIDNEY组织的水动力学方法及相关材料和方法
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申请号: PCT/US2013/039454申请日: 2013-05-03
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公开(公告)号: WO2013166378A1公开(公告)日: 2013-11-07
- 发明人: BACALLAO, Robert , ATKINSON, Simon , RHODES, George , CORRIDON, Peter
- 申请人: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
- 申请人地址: 351 W. 10th Street Suite 210 Indianapolis, IN 46202 US
- 专利权人: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
- 当前专利权人: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
- 当前专利权人地址: 351 W. 10th Street Suite 210 Indianapolis, IN 46202 US
- 代理机构: JOHNSON, Kristine, H.
- 优先权: US61/642,203 20120503; US61/680,757 20120808; US61/770,848 20130228
- 主分类号: A61K38/18
- IPC分类号: A61K38/18 ; C12N15/00
摘要:
The present invention provides methods and materials useful delivering liquids, including liquids comprising nucleic acid molecules into cells. In particular, the present invention provides methods for delivering saline solution, exogenous compositions, and isolated vectors to kidney cells, using the renal vein as a guide and under hydrodynamic pressure. The delivery methods and materials herein are useful to research, prognose, ameliorate symptoms of kidney injury, and treat kidney pathologies.
IPC分类: