Green technology method is described a combination of prototype processing for the preparation, purification and modification of micro- and nano-size scale clay particles from mineral resources of Turkey using novel functional organic intercalants as reactive nanofillers, alternating copolymers of maleic anhydride and their grafts with biopolymers as reactive compatibilizers and bioactive matrix polymers, thermoplastics, thermosets and rubbers as processible matrix polymers, which are useful for preparation of novel high performance engineering and bioengineering polymer layered silicate nanomaterials (nanofims, nanocoatings, nanofibers, nanomedicals and etc.).