Invention Application
- Patent Title: TREATMENT OF AUTOPHAGY-RELATED DISORDERS
- Patent Title (中): 治疗自身免疫性疾病
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Application No.: PCT/US2014/039979Application Date: 2014-05-29
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Publication No.: WO2014200705A1Publication Date: 2014-12-18
- Inventor: DERETIC, Vojo, P. , MANDELL, Michale
- Applicant: STC.UNM , DERETIC, Vojo, P. , MANDELL, Michale
- Applicant Address: 801 University Blvd. Se, Suite 101 Albuquerque, NM 87106 US
- Assignee: STC.UNM,DERETIC, Vojo, P.,MANDELL, Michale
- Current Assignee: STC.UNM,DERETIC, Vojo, P.,MANDELL, Michale
- Current Assignee Address: 801 University Blvd. Se, Suite 101 Albuquerque, NM 87106 US
- Agency: COLEMAN, Henry, D.
- Priority: US61/835,227 20130614; US61/835,255 20130614
- Main IPC: C12N9/00
- IPC: C12N9/00
Abstract:
The present invention relates to the use of neutral lipids, including triglycerides, diglycerides and monoglycerides which may be used to increase neutral lipids (lipid stores and/or lipid droplets) and neutral lipid stores in order to regulate (in particular, induce) autophagy and treat and/or prevent autophagy related disease states and/or conditions. In one embodiment, the invention relates to the use of neutral lipids and/or TRIM proteins which may be used to regulate (in particular, induce) autophagy, target autophagic substrates and treat and/or prevent autophagic disease states and/or conditions.
Information query
