Invention Application
WO2015070187A2 SYSTEMS AND METHODS FOR UNIVERSAL TAIL-BASED INDEXING STRATEGIES FOR AMPLICON SEQUENCING
审中-公开
用于AMPLICON序列的通用基于尾段的指数策略的系统和方法
- Patent Title: SYSTEMS AND METHODS FOR UNIVERSAL TAIL-BASED INDEXING STRATEGIES FOR AMPLICON SEQUENCING
- Patent Title (中): 用于AMPLICON序列的通用基于尾段的指数策略的系统和方法
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Application No.: PCT/US2014/064890Application Date: 2014-11-10
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Publication No.: WO2015070187A2Publication Date: 2015-05-14
- Inventor: SCHUPP, James M. , COLMAN, Rebecca , ENGELTHALER, David , GILLECE, John , HICKS, Nathan , KEIM, Paul S.
- Applicant: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
- Applicant Address: 445 North Fifth Street Suite 600 Phoenix, Arizona 85004 US
- Assignee: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
- Current Assignee: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
- Current Assignee Address: 445 North Fifth Street Suite 600 Phoenix, Arizona 85004 US
- Agency: FULLER, Rodney J
- Priority: US61/902,432 20131111
- Main IPC: A61B3/10
- IPC: A61B3/10
Abstract:
Some embodiments of the invention include a method of preparing a sample for sequencing that includes receiving a sample and amplifying at least one marker within the sample. In some embodiments, amplification of the first marker may include mixing the sample with a first oligonucleotide that comprises a first universal tail sequence and a second oligonucleotide that comprises a second universal tail sequence. In some aspects of the invention, the first universal tail sequence and the second universal tail sequence are different sequences.
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