发明申请
- 专利标题: COMPOUNDS AND METHODS OF USE
- 专利标题(中): 化合物和使用方法
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申请号: PCT/US2014/072922申请日: 2014-12-31
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公开(公告)号: WO2015103355A1公开(公告)日: 2015-07-09
- 发明人: RAI, Roopa , CHAKRAVARTY, Sarvajit , PUJALA, Brahmam , SHINDE, Bharat Uttam , NAYAK, Anjan Kumar , CHAKLAN, Naveen , AGARWAL, Anil Kumar , RAMACHANDRAN, Sreekanth A. , PHAM, Son
- 申请人: MEDIVATION TECHNOLOGIES, INC.
- 申请人地址: 525 Market Street 36th floor San Francisco, California 94105 US
- 专利权人: MEDIVATION TECHNOLOGIES, INC.
- 当前专利权人: MEDIVATION TECHNOLOGIES, INC.
- 当前专利权人地址: 525 Market Street 36th floor San Francisco, California 94105 US
- 代理机构: HEMMENDINGER, Lisa M.
- 优先权: IN6/DEL/2014 20140101
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D401/12 ; C07D471/04 ; C07D487/04 ; A61K31/445 ; A61P35/00
摘要:
This disclosure provides compounds and compositions and methods of using those compounds and compositions to treat diseases and disorders associated with excessive transforming growth factor-beta (TGFβ) activity. This disclosure also provides methods of using the compounds in combination with one or more cancer immunotherapies.