发明申请
- 专利标题: 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS
- 专利标题(中): 3,5-二氨基吡唑激酶抑制剂
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申请号: PCT/US2015/067359申请日: 2015-12-22
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公开(公告)号: WO2016106309A1公开(公告)日: 2016-06-30
- 发明人: LY, Tai, Wei
- 申请人: AXIKIN PHARMACEUTICALS, INC.
- 申请人地址: 4940 Carroll Canyon Road, Suite 100 San Diego, CA 92121 US
- 专利权人: AXIKIN PHARMACEUTICALS, INC.
- 当前专利权人: AXIKIN PHARMACEUTICALS, INC.
- 当前专利权人地址: 4940 Carroll Canyon Road, Suite 100 San Diego, CA 92121 US
- 代理机构: RIEGER, Dale, L. et al.
- 优先权: US62/096,308 20141223
- 主分类号: C07D403/12
- IPC分类号: C07D403/12 ; C07D231/14 ; C07D401/12 ; C07D403/14 ; C07D413/12 ; C07D417/12 ; A61P11/00 ; A61K31/415 ; A61K31/4439 ; A61K31/496 ; A61K31/5377 ; A61K31/541
摘要:
Provided herein are 3,5-diaminopyrazoles, for example, compounds of Formula (I), that are useful for modulating regulated-in-COPD kinase activity, and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a RC kinase-mediated disorder, disease, or condition.