Invention Application
- Patent Title: DESORPTION ELECTROSPRAY IONISATION ("DESI") IMAGING
- Patent Title (中): 解密电子放映（“DESI”）成像
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Application No.: PCT/GB2016/050624Application Date: 2016-03-07
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Publication No.: WO2016142694A1Publication Date: 2016-09-15
- Inventor: PRINGLE, Steven Derek , JONES, Emrys , O'BRIEN, Stephen , TAKÁTS, Zoltán
- Applicant: MICROMASS UK LIMITED
- Applicant Address: Stamford Avenue Altrincham Road Wilmslow SK9 4AX GB
- Assignee: MICROMASS UK LIMITED
- Current Assignee: MICROMASS UK LIMITED
- Current Assignee Address: Stamford Avenue Altrincham Road Wilmslow SK9 4AX GB
- Agency: JEFFREY, Philip Michael
- Priority: GB1503879.7 20150306; GB1503876.3 20150306; GB1503864.9 20150306; GB1503877.1 20150306; GB1503867.2 20150306; GB1503863.1 20150306; GB1503878.9 20150306; GB1516003.9 20150909; GB1518369.2 20151016
- Main IPC: G01N33/68
- IPC: G01N33/68
Abstract:
A method is disclosed comprising applying a reversal agent, such as urea, to a formalin fixed tissue sample in order to reverse the effects of the fixation process. An ambient ionisation ion source such as a desorption electrospray ionisation ("DESI") ion source is used to generate analyte or analyte ions from multiple regions of the modified target so that an ion image of the modified target may be generated.
Information query
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