发明申请
- 专利标题: AXL-SPECIFIC ANTIBODY-DRUG CONJUGATES FOR CANCER TREATMENT
- 专利标题(中): 用于癌症治疗的AXL特异性抗体药物联合
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申请号: PCT/EP2016/066353申请日: 2016-07-08
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公开(公告)号: WO2017009258A1公开(公告)日: 2017-01-19
- 发明人: BOSHUIZEN, Julia , JACOBSEN, Kirstine , BREIJ, Esther , KOOPMAN, Louise , SATIJN, David , VAN DEN BRINK, Edward , VERZIJL, Dennis , DE JONG, Rob , VAN DIJKHUIZEN RADERSMA, Riemke , PEEPER, Daniel , DITZEL, Henrik Jørn , PARREN, Paul
- 申请人: GENMAB A/S
- 申请人地址: Bredgade 34 E 1260 Copenhagen K DK
- 专利权人: GENMAB A/S
- 当前专利权人: GENMAB A/S
- 当前专利权人地址: Bredgade 34 E 1260 Copenhagen K DK
- 代理机构: GENMAB A/S
- 优先权: EPPCT/EP2015/065900 20150710; US62/278,283 20160113
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K47/48 ; A61P35/00
摘要:
The present disclosure relates to antibody-drug conjugates (ADCs) binding to human AXL for therapeutic use, particularly for treatment of resistant or refractory cancers.