Invention Application
WO2017009710A2 DYNAMIC FORMATION OF NANOCHANNELS FOR SINGLE-MOLECULE DNA ANALYSIS
审中-公开
用于单分子DNA分析的纳米通道的动态形成
- Patent Title: DYNAMIC FORMATION OF NANOCHANNELS FOR SINGLE-MOLECULE DNA ANALYSIS
- Patent Title (中): 用于单分子DNA分析的纳米通道的动态形成
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Application No.: PCT/IB2016/001045Application Date: 2016-06-30
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Publication No.: WO2017009710A2Publication Date: 2017-01-19
- Inventor: YAO, Shuhuai , YU, Miao , HOU, Youmin
- Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Applicant Address: Technology Transfer Center Clear Water Bay, Kowloon Hong Kong CN
- Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: Technology Transfer Center Clear Water Bay, Kowloon Hong Kong CN
- Priority: US62/193,542 20150716
Abstract:
Devices having nanochannels suitable for confinement and alignment of DNA molecules, as well as methods of fabricating the same and methods of using the same for DNA analysis, are provided. A device can include a dynamically-controlled, unified microchannel-nanochannel platform suitable for confinement and alignment of DNA molecules. The nanochannels can be reversibly formed within nanoslits formed in a deformable substrate or base layer.
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