发明申请
WO2017019673A2 METHODS FOR DIAGNOSING AND TREATING INFLAMMATORY BOWEL DISEASE
审中-公开
用于诊断和治疗炎症性皮肤病的方法
- 专利标题： METHODS FOR DIAGNOSING AND TREATING INFLAMMATORY BOWEL DISEASE
- 专利标题（中）： 用于诊断和治疗炎症性皮肤病的方法
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申请号： PCT/US2016/044022申请日： 2016-07-26
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公开(公告)号： WO2017019673A2公开(公告)日： 2017-02-02
- 发明人: MONTAGUT, Teresa Ramirez , CHAI, Akiko , FUH, Franklin
- 申请人： GENENTECH, INC. , F. HOFFMANN-LA ROCHE AG
- 申请人地址： 1 DNA Way South San Francsico, California 94080 US
- 专利权人： GENENTECH, INC.,F. HOFFMANN-LA ROCHE AG
- 当前专利权人： GENENTECH, INC.,F. HOFFMANN-LA ROCHE AG
- 当前专利权人地址： 1 DNA Way South San Francsico, California 94080 US
- 代理机构： SCARR, Rebecca B. et al.
- 优先权： US62/197,293 20150727; US62/241,331 20151014
- 主分类号： G01N33/50
- IPC分类号： G01N33/50
摘要：
Biomarkers predictive of responsiveness to integrin beta7 antagonists, including anti-beta7 integrin subunit antibodies, and methods of using such biomarkers are provided. In addition, methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases including ulcerative colitis and Crohn's disease are provided. Also provided are methods of using such predictive biomarkers for the treatment of inflammatory bowel diseases including ulcerative colitis and Crohn's disease.
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