发明申请
WO2017062496A3 ANTI-SAS1B ANTIBODIES, ASSOCIATED METHODS OF USE, AND COMPOSITIONS AND METHODS FOR DETECTING AND TREATING CANCER
审中-公开
抗SAS1B抗体，相关的使用方法以及检测和治疗癌症的组合物和方法
- 专利标题： ANTI-SAS1B ANTIBODIES, ASSOCIATED METHODS OF USE, AND COMPOSITIONS AND METHODS FOR DETECTING AND TREATING CANCER
- 专利标题（中）： 抗SAS1B抗体，相关的使用方法以及检测和治疗癌症的组合物和方法
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申请号： PCT/US2016055557申请日： 2016-10-05
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公开(公告)号： WO2017062496A3公开(公告)日： 2017-06-01
- 发明人: HERR JOHN , PIRES EUSEBIO , D'SOUZA RYAN , MANDAL ARABINDA , ANDERSON-KNAPP KILEY
- 申请人： UNIV VIRGINIA PATENT FOUNDATION , HERR JOHN , PIRES EUSEBIO , D'SOUZA RYAN , MANDAL ARABINDA , ANDERSON-KNAPP KILEY
- 专利权人： UNIV VIRGINIA PATENT FOUNDATION,HERR JOHN,PIRES EUSEBIO,D'SOUZA RYAN,MANDAL ARABINDA,ANDERSON-KNAPP KILEY
- 当前专利权人： UNIV VIRGINIA PATENT FOUNDATION,HERR JOHN,PIRES EUSEBIO,D'SOUZA RYAN,MANDAL ARABINDA,ANDERSON-KNAPP KILEY
- 优先权： US201562237211 2015-10-05; US201662298944 2016-02-23; US201662358453 2016-07-05
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K38/17 ; A61K39/00 ; C12Q1/68 ; G01N33/574 ; G01N33/68
摘要：
The present disclosure provides anti-SAS1B antibodies, antigen-binding fragments thereof, and antibody-drug conjugates and methods of their use. This present disclosure also provides an isolated antibody or antigen-binding portion thereof having at least one of SB antibodies binding to surface exposed SAS1B, and 6B1 antibodies identifying at least one set of cancer patients testing positive for SAS1B expression.
