Invention Application
WO2017066487A1 APPARATUS AND METHOD FOR MEASUREMENTS OF GROWTH OR DISSOLUTION KINETICS OF COLLOIDAL PARTICLES 审中-公开
用于测量胶体颗粒的生长或溶解动力学的装置和方法

  • Patent Title: APPARATUS AND METHOD FOR MEASUREMENTS OF GROWTH OR DISSOLUTION KINETICS OF COLLOIDAL PARTICLES
  • Patent Title (中): 用于测量胶体颗粒的生长或溶解动力学的装置和方法
  • Application No.: PCT/US2016/056909
    Application Date: 2016-10-13
  • Publication No.: WO2017066487A1
    Publication Date: 2017-04-20
  • Inventor: TATARKIEWICZ, Jan, J.KARR, Monette
  • Applicant: MANTA INSTRUCTIONS, INC.
  • Applicant Address: 9191 Towne Centre Dr, Suite 330 San Diego, CA 92122 US
  • Assignee: MANTA INSTRUCTIONS, INC.
  • Current Assignee: MANTA INSTRUCTIONS, INC.
  • Current Assignee Address: 9191 Towne Centre Dr, Suite 330 San Diego, CA 92122 US
  • Agency: DE LA CERRA, Manuel
  • Priority: US62/241,354 20151014; US15/018,532 20160208; US15/194,823 20160628
  • Main IPC: G01N15/02
  • IPC: G01N15/02
APPARATUS AND METHOD FOR MEASUREMENTS OF GROWTH OR DISSOLUTION KINETICS OF COLLOIDAL PARTICLES
Abstract:
A system for determining the growth/dissolution rate of colloidal particles is disclosed and includes multiple light sources and multiple sensors. A light source is constructed to emit a beam of electromagnetic radiation at a specimen chamber that holds the colloidal particles. The chamber allows a portion of the combined beam to scatter perpendicularly or at some other angle to the combined beam. The scattered portion of the beam is directed to a sensor that detects electromagnetic radiation. The sensor is connected to processor that activates the light source and obtains an image from the sensor. Multiple images are taken at a time interval and for each image taken, and a total image intensity level is calculated and normalized. A formula is then calculated that fits the normalized values over time and a slope is determined from the formula.
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