发明申请
- 专利标题: GLYCAN-INTERACTING COMPOUNDS AND METHODS OF USE
- 专利标题(中): 糖苷相互作用化合物和使用方法
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申请号: PCT/US2016/061427申请日: 2016-11-10
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公开(公告)号: WO2017083582A1公开(公告)日: 2017-05-18
- 发明人: EAVARONE, David A. , PRENDERGAST, Jillian M. , BEHRENS, Jeffrey , LUGOVSKOY, Alexey Alexandrovich , DRANSFIELD, Daniel T.
- 申请人: SIAMAB THERAPEUTICS, INC.
- 申请人地址: 90 Bridge Street Suite 100 Newton, Massachusetts 02458 US
- 专利权人: SIAMAB THERAPEUTICS, INC.
- 当前专利权人: SIAMAB THERAPEUTICS, INC.
- 当前专利权人地址: 90 Bridge Street Suite 100 Newton, Massachusetts 02458 US
- 代理机构: WARD, Donna T. et al.
- 优先权: US62/254,278 20151112; US62/274,572 20160104; US62/287,666 20160127; US62/293,989 20160211; US62/345,515 20160603; US62/382,835 20160902
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/00 ; C07K16/30 ; G01N33/574
摘要:
The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include humanized antibodies, derivatives and fragments thereof as well as related compositions and kits. Methods of using glycan-interacting antibodies for treatment and diagnosis are included.