- 专利标题： INHIBITORS OF BACTERIAL RNA POLYMERASE: ARYLPROPANOYL, ARYLPROPENOYL, AND ARYLCYCLOPROPANECARBOXYL PHLOROGLUCINOLS
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申请号： PCT/US2016/065931申请日： 2016-12-09
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公开(公告)号： WO2017100645A2公开(公告)日： 2017-06-15
- 发明人: EBRIGHT, Richard H. , FREUNDLICH, Joel , MITTAL, Nisha , JASKOWSKI, Mark , SHEN, Juan
- 申请人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY , EBRIGHT, Richard H. , FREUNDLICH, Joel , MITTAL, Nisha , JASKOWSKI, Mark , SHEN, Juan
- 申请人地址： Old Queens Building, Somerset and George Streets New Brunswick, New Jersey 08901 US
- 专利权人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY,EBRIGHT, Richard H.,FREUNDLICH, Joel,MITTAL, Nisha,JASKOWSKI, Mark,SHEN, Juan
- 当前专利权人： RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY,EBRIGHT, Richard H.,FREUNDLICH, Joel,MITTAL, Nisha,JASKOWSKI, Mark,SHEN, Juan
- 当前专利权人地址： Old Queens Building, Somerset and George Streets New Brunswick, New Jersey 08901 US
- 代理机构： HARRIS, Robert J. et al.
- 优先权： US62/265,881 20151210
- 主分类号： A61K31/381
- IPC分类号： A61K31/381 ; A61K31/12
摘要：
The invention provides compounds that are inhibitors of bacterial RNA polymerase. The invention also provides compositions comprising such compounds, methods of making such compounds, and methods of using said compounds. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy.
公开/授权文献
