System(100) for calibrating particulate matter sensors includes a chamber(102) including a plurality of particulate matter sensors(104-1,104-2,104-3,104-N), a fan(110), a particulate matter source(108), an air cleaner(112), and a reference particulate matter sensor(106), a computing device(114) having a processor(118) and a memory(116) storing instructions which, when executed by the processor(118), cause the processor(118) to activate the particulate matter source(108) and the fan(110) until the reference concentration reaches a threshold, activate the air cleaner(112) responsive to the threshold being reached until the reference concentration reaches a calibration point, receive a respective determined mass concentration from each of the plurality of particulate matter sensors(104-1,104-2,104-3,104-N) at the calibration point, and calibrate each of the plurality of particulate matter sensors(104-1,104-2,104-3,104-N) based, at least in part, on a respective relationship between the reference concentration and each determined mass concentration at the calibration point. Methods and devices for calibrating particulate matter sensors are also described.