Invention Application
WO2017118968A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS
审中-公开
氨基糖苷衍生物及其在治疗遗传性疾病中的用途
- Patent Title: AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS
- Patent Title (中): 氨基糖苷衍生物及其在治疗遗传性疾病中的用途
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Application No.: PCT/IL2016/050969Application Date: 2016-09-02
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Publication No.: WO2017118968A1Publication Date: 2017-07-13
- Inventor: BAASOV, Timor , TUVIA, Shmuel
- Applicant: ELOXX PHARMACEUTICALS LTD.
- Applicant Address: 7 Golda Meir Street 7403650 Nes Ziona IL
- Assignee: ELOXX PHARMACEUTICALS LTD.
- Current Assignee: ELOXX PHARMACEUTICALS LTD.
- Current Assignee Address: 7 Golda Meir Street 7403650 Nes Ziona IL
- Agency: EHRLICH, Gal et al.
- Priority: US62/274,915 20160105
- Main IPC: C07H15/23
- IPC: C07H15/23 ; A61K31/7036 ; A61P7/04 ; A61P21/00 ; A61P21/04 ; C07H15/222 ; C07H15/224
Abstract:
Novel aminoglycosides, represented by Formulae (I), (Ia), (III) and (IIIa), as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic diseases and disorders, such as diseases and disorders associated with stop codon mutations.
Information query
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