发明申请
WO2017120507A1 NOVEL COMPOUNDS WHICH ACTIVATE ESTROGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USING THE SAME
审中-公开
激活雌激素受体和组合物的新化合物及使用该化合物的方法
- 专利标题： NOVEL COMPOUNDS WHICH ACTIVATE ESTROGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USING THE SAME
- 专利标题（中）： 激活雌激素受体和组合物的新化合物及使用该化合物的方法
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申请号： PCT/US2017/012586申请日： 2017-01-06
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公开(公告)号： WO2017120507A1公开(公告)日： 2017-07-13
- 发明人: KATZENELLENBOGEN, John , KATZENELLENBOGEN, Benita , KIM, Sung Hoon , MADAK-ERDOGAN, Zeynep , SHAUL, Philip
- 申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER , KATZENELLENBOGEN, John , KATZENELLENBOGEN, Benita , KIM, Sung Hoon , MADAK-ERDOGAN, Zeynep , SHAUL, Philip
- 申请人地址： 352 Henry Administrative Building 506 S. Wright St. Urbana, Illinois 61801 US
- 专利权人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS,THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER,KATZENELLENBOGEN, John,KATZENELLENBOGEN, Benita,KIM, Sung Hoon,MADAK-ERDOGAN, Zeynep,SHAUL, Philip
- 当前专利权人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS,THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER,KATZENELLENBOGEN, John,KATZENELLENBOGEN, Benita,KIM, Sung Hoon,MADAK-ERDOGAN, Zeynep,SHAUL, Philip
- 当前专利权人地址： 352 Henry Administrative Building 506 S. Wright St. Urbana, Illinois 61801 US
- 代理机构： YAGER, Charlene, L. et al.
- 优先权： US62/275,416 20160106
- 主分类号： A61P35/00
- IPC分类号： A61P35/00 ; A61K31/00 ; C07K14/705 ; G01N33/574
摘要：
Provided are compounds of formulae provided herein. The compounds may include pathway-preferential estrogens (PaPEs) derivatives with tissue-selective activities. Also provided are pharmaceutical compositions comprising the compounds, as well as methods of treating a disease or condition including administering the compounds. The disease or condition may include postmenopausal symptoms, cardiovascular disease, stroke, vascular disease, bone disease, metabolic disease, arthritis, osteoporosis, obesity, vasomotor/hot flush, cognitive decline, cancer including breast cancer.
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P35/00 | 抗肿瘤药 |
